General Information on Nexium (Esomeprazole)
This drug is an antacid, anti- ulcer.
Belongs to the class Proton Pump Inhibitors
The IUPAC name is (S)-5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)
methylsulfinyl]-3H-benzoimidazole
The brand Nexium is manufactured and marketed by the the Astra Zeneca pharmaceutical company.
Nexium pill is available as purple pill with stripes.
The other brands available are Sompraz, Zoleri, Lucen, Esopral, Axion and Nexium.
Pharmacology
The formula of Nexium is C17 H19 N3 O3 S
Physical Properties of Nexium- Esomeprazole is white crystalline powder, soluble in water, dissolves quickly in acid medium
Has good bio-availability 60- 90%
Bound to protein 97%
Metabolizes in Liver by Cytochrome P 2C19, CYP 3A4 and is excreted in urine.
The half life or the effect of the drug in our body is 1 hour, duration of action is for 24 hours
Hence can be taken once daily
Usage/ Indication and Dosage
Nexium is available in the following strengths
Nexium 20 mg and Nexium 40 mg
The appropriate Dosage will be calculated by your physician depending upon your condition
Nexium is also available in combination with Domperidone.
The maximum dose of Nexium available now is 40 mg
The indications are viz;
Acid peptic disease,
gastric Ulcer,
Duodenal ulcer,
Heartburn,
In GERD gastro-esophageal reflux disease, which is nothing but the feeling of heat burn and sour taste in your throat after you burp, if happens rarely not an issue though, but if happens regularly, then this is the tablet you should be taking.
In H-Pylori infection, along with the anti-biotic you will be given this drug or better results
When taken along with domperidone, this combination promotes digestion and prevents heartburn.
Treatment is usually for 4- 8 weeks, except for conditions like zollinger Ellison disease, where the acid production in the stomach is always high.
Mechanism of Action
Acts by inhibiting/stopping the release of acid through Proton Pumps present in the stomachs parietal cell, which are responsible for the acid release.
Side/ Adverse effects of Nexium
Rashes, allergy reaction, if the patient is allergic to Esomeprazole and related compounds.
The other un-common undesired effects are drowsiness, headache, nausea, gas trouble, flu like symptoms, pharyngitis, constipation and rarely infection.
Precaution and contra indication
Hypersensitivity
Pediatric age group
Hepatic and renal disease
Pregnancy B
Malignancy
To be used in caution when patients are taking warfarin
Where and how to buy Nexium
Buying or ordering Nexium was never been easier and safer than this, Buy generic Nexium from genuine online seller which shows certifications and good testimonials. All you have to do is log in to our web site and register, You can buy generic Nexium 20 mg, 40 mg. After logging in, select the generic Nexium and Order Nexium online along with the strength and quantity. Should you have any discount coupon, do enter the code in the appropriate column.
Do not worry even if you dont have a prescription, Our online physicians will take a brief history and issue the prescription. In emergency you can have generic nexium or generic esomeprazole without prescription. Then follow the instructions prompted by the website
We will guarantee you a safe and secure transaction through your online purchase.
You are guaranteed to get the best quality and cheap Nexium from our online store.
Wish you a speedy recover
|
