General Information on Prevacid (Lansoprazole)
This drug is an antacid, anti- ulcer.
The generic name for this drug is Lansoprazole.
Belongs to the class Proton Pump Inhibitors
The IUPAC name is (RS)-2-([3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl)-1H-benzo[d]imidazole
The brand Prevacid is manufactured and marketed by the Takeda pharmaceutical company.
The other brands available are Helicid, Zoton, Inhibitol
The prevacid pill is pink and turquoise in color and comes as capsules.
Pharmacology
The formula of Prevacid is C16 H14 N3 O2 S
Physical Properties of Prevacid- Lansoprazole is brownish- white odorless crystalline powder, insoluble in water, soluble in alcohol, dissolves quickly in acid medium
Has good bio-availability 60- 90%
Bound to protein 97%
Metabolizes in Liver and is excreted in urine.
The half life or the effect of the drug in our body is 1 hour, duration of action is for 24 hours
Hence can be taken once daily
Usage/ Indication and Dosage
Prevacid is available in the following strengths
Generic Prevacid lansoprazole 15 mg and Prevacid 30 mg or Lansoprazole 30 mg
The appropriate Dosage will be calculated by your physician depending upon your condition
The maximum dose of Prevacid available now is 30 mg
The indications are viz;
Acid peptic disease,
gastric Ulcer,
Duodenal ulcer,
Heartburn,
In GERD gastro-esophageal reflux disease, which is nothing but the feeling of heat burn and sour taste in your throat after you burp, if happens rarely not an issue though, but if happens regularly, then this is the tablet you should be taking.
In H-Pylori infection, along with the anti-biotic you will be given this drug or better results
When taken along with domperidone, this combination promotes digestion and prevents heartburn.
Treatment is usually for 4- 8 weeks, except for conditions like zollinger Ellison disease, where the acid production in the stomach is always high.
Mechanism of Action
Acts by inhibiting/ stopping the release of acid through Proton Pumps present in the stomachs parietal cell, which are responsible for the acid release.
Side/ Adverse effects of Prevacid
Rashes, allergy reaction, if the patient is allergic to lansoprazole and related compounds.
The other un-common undesired effects are drowsiness, headache, nausea, gas trouble, loose bowel movement and rarely infection.
Precaution and contra indication
Hypersensitivity
Pediatric age group
Hepatic and renal disease
Pregnancy B
Malignancy
To be used in caution when patients are taking warfarin
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