Rulide for the treatment of Soft Tissue Infections of the Respiratory or Urinary Tracts
Rulide is a macrolide antibiotic that is semi-synthetic. Derived from erythromycin, generic rulide or roxithromycin is used to treat soft tissue infections of the urinary or respiratory tracts. Currently this drug is being studied in a clinical trial as a potential treatment for male pattern hair loss as well as use as an antimalarial. You can find more information about the studies of rulide online.
There are a number of brand names you can find roxithromycin; they include, Rulide, Roxo, Biaxsig, Surlid, Roxar, Roxomycin, Roximycin, Coroxin and Triabicin. Currently Roxithromycin is not available in the US however you can order rulide. Competition and the variety of brands available make cheap rulide easy to find.
Hoechst Uclaf a German pharmaceutical company bought Roxithromycin in 1987. You can buy rulide in a variety of forms including tablets and oral suspensions. The way this medicine works is that it interferes with the synthesis of proteins and prevents bacteria from growing. Working to bind the 50S subunit of the ribosome bacteria and therefore inhibiting peptides from translocating. Similar to erythromycin in the spectrum of antimicrobials however it is been demonstrated to be more effective in fighting gram-negative bacteria including Legionella pneumophila.
It is recommended that you take rulide prior to eating a meal. This allows the active ingredients to be readily absorbed and diffused into the phagocytes and tissue. High concentrations of phagocytes help to actively transport the medicine to the site of the infection. This allows for large concentrations of the medicine to be released to fight the infection. Very little of the drug is metabolized with most of it being secreted in to the bile or expired into the air. Less than ten percent is found in the urine. The half-life of rulide is twelve hours.
Common side effects of rulide 150 mg include nausea, diarrhea, abdominal pain or vomiting. Less common include peripheral or central nervous system issues including vertigo, headaches, dizziness as well as abnormal liver function, rash and changes in the sense of taste or smell. You buy cheap rulide if you compare prices.
Rulide has less issues associated with interactions than erythromycin as well as a lower affinity than cytochrome P450. It will not interact with prednisolone, rantidine, hormonal contraceptives, antacids or carbamazepine. With rulide is combined with theophylline several studies have indicated an increase in the concentration of theophylline in plasma. This may require a change in dosing if you have a higher level of theophylline when you begin treatment. These findings indicate that the theophylline levels should be monitored when taking rulide.
It is also possible that roxithromycin interacts with warfarin by increasing the prothrombin time level. If you take warfarin and are on rulide you may experience episodes of severe bleeding.
Dosing and efficacy are determined by age and weight. The average adult is administered 300 mg per day. General recommendation suggests taking one tablet with a glass of water.